Harris, who wields a tie-breaking vote in the Senate, plans to work in person starting on Tuesday.
Doug Emhoff, Harris' husband, told reporters that the vice president is feeling fine.
"She's doing great," he said on the sidelines of a White House reception marking the Muslim Eid al-Fitr holiday. "She worked the entire time."
She will continue to wear a mask through the 10-day period following a negative rapid antigen test, under Centers for Disease Control and Prevention guidelines, spokesperson Kirsten Allen said in a statement.
The White House announced Harris' positive result last Tuesday.
Senate Democrats have had to delay efforts to advance President Joe Biden's nominees for the Federal Reserve and Federal Trade Commission in recent weeks.
Recent COVID cases, including Harris and three Democratic senators, threatened further delays. The Senate is split evenly between members aligned with Democrats and Republicans.
Sweden and Finland have formally submitted their applications to join Nato, in one of the biggest geopolitical consequences to date of Russia’s invasion of Ukraine.