"We reached the goal for patients like me, who aren't terminal but degenerative, to win this battle, a battle that opens the doors for the other patients who come after me and who right now want a dignified death," Escobar, 60, said in a video message sent to media by Giraldo.
On Saturday, a second Colombian -- a woman with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease -- was also euthanized.
Escobar suffered from end-stage chronic obstructive pulmonary disease, which greatly diminishes quality of life, as well as a number of other conditions, Giraldo told Reuters.
The procedure took place in a clinic in Cali, the capital city of Colombia's Valle del Cauca province.
"I'm not saying goodbye, just 'see you later,'" Escobar said.
Escobar had fought two years for his right to euthanasia in the face of opposition from doctors, clinics and courts, even though the Constitutional Court last year recognized the procedure should not be available just for the terminally ill.
On Saturday, Martha Sepulveda underwent the procedure in the city of Medellin at midday; DescLAB -- who supported her case -- said in a statement.
Sepulveda -- who had been diagnosed with Lou Gehrig's disease in 2018 -- was due to be euthanized on October 10 last year, but the procedure was halted at the 11th hour.
Colombia's Constitutional Court removed penalties for euthanasia under certain circumstances in 1997 and ordered the procedure to be regulated in 2014.
The first person in Colombia with a terminal illness to die under those rules was in 2015.
As of October 15 last year, 178 people with terminal illnesses had been legally euthanized in Colombia since 2015, according to Colombian legal rights advocacy group DescLAB.
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